Somatic chromosome mutations and morphological abnormalities in sperms of boars

Assessment of Morphological and Functional Changes in the Mouse Testis and Epididymal Sperms Following Busulfan Treatment

Busulfan, a cytotoxic drug, which is currently used as a chemotherapeutic agent, has many side effects on different body organs. In this research, the effects of busulfan on sperm parameters and microstructure of mouse testis were investigated. Methods: Busulfan was injected intrapretoneally at 10, 20, 30, 40 and 50 mg/kg and testes were removed after 4, 6 and 8 weeks, weighed and processed fo...

Experiments on Mutations Induced by Neutrons in Drosophila Melanogaster Sperms.

WO somewhat puzzling phenomena have been reported in the literature T on neutron-induced lethals in Drosophila. NAGAI and LOCHER (1938), in the first work on this subject, kept the offspring of different neutron-treated males separate during the tests for sex-linked lethals and reported that the lethals were not distributed a t random among the offspring of different males. Two or more lethals ...

Practice of Consanguinity and Unusual Cases of Inherited Familial Chromosome Abnormalities: A Case Report

We present 2 cases of likely rare event. In case 1, 3rd degree consanguineous marriage revealed inv(6) with same break points in parents who were found to be phenotypically normal. The same inv(6) being inherited in progeny but presented with low AMH (anti Mullerian hormone) and high level of FSH (follicular stimulating hormone) leading to polycystic ovarian syndrome/premature ovarian failure. ...

Lysergide and chromosome abnormalities.

Chromosome Abnormalities in Leukemia

The renewed interest in the study of chromosome abnormalities in hematologic malignancies, particularly in the leukemias, is the result of technical improvements which permit the precise identification of each human chromosome, and of parts of chromosomes as well. The information obtained raises a number of questions regarding the validity of older notions, such as the variability of the chromo...